The purpose of this study was to determine and design a structural model of the relationship between organizational virtue and organizational justice with the mediating role of professional ethics among faculty members and staffs of Payam-e-Noor universities in Khuzestan province. METHOD: The research method was descriptive-correlational which was performed in 2017-2018 academic years. The study population consisted of all faculty members and staffs of Payam-eNoor Universities in Khuzestan province (720 persons) that sample size (295) was estimated by stratified random sampling based on sample size using Krejcie and Morgan table. Organizational Justice Scale(Niehoff and Moorman,1993), Organizational Virtue Scale(Cameron et al. , 2004) and Professional Ethics Questionnaire (Cadozier, 2002) have been used that the coefficient of reliability of Cronbach's alpha was 0. 94, 0. 93 and 0. 83, respectively. Descriptive statistics and structural equation modeling were used for data analysis using SPSS24 and AMOSE statistical software. RESULTS: The results showed that (a); the direct effect of organizational virtue on organizational justice was statistically significant (R=0. 74), (B); the direct effect of organizational virtue and professional ethics was statistically significant (R= 0. 31). (C); The direct effect of professional ethics on organizational justice was statistically significant (R = 0. 16). Finally, the indirect effect of the organizational virtue of organizational justice was not statistically significant. CONCLUSION: professional ethics do not mediate the relationship between organizational virtue and organizational justice. Also, in an atmosphere of trust, honesty, and optimism, employees avoid engaging in unproductive and unethical behaviors caused by immorality and they are turning to produce work that provides them with the opportunity to learn and grow to promote organizational justice